Overview
Recent studies from the lab (https://cruchagalab.wustl.edu/) have demonstrated that circular RNAs (circRNAs) are associated with Alzheimer’s disease status and when measuring in blood can be used as disease biomarkers.
We have generated brain and blood transcriptomic data in thousands of samples with several neurodegenerative diseases with emphasis on Alzheimer’s disease, Parkinson’s disease, and other dementias with the goal of understanding the biology of these diseases, to define novel biomarkers, and to identify novel therapeutical targets.
We are hiring a postdoc to work with RNA-seq data in order to identify circRNA implicated in complex traits including Alzheimer’s disease, Parkinson’s disease and stroke using novel and integrative computational and statistical analyses.
The candidate will hold a PhD in statistics, Bioinformatics, Computational Biology, Biostatistics, Statistical Genetics, Medical Statistics, Mathematics or similar. The candidate should have a strong background in second-generation sequencing analyses (RNA) with focus on circRNAs, pathways analyses and biomarker discovery. Knowledge of GWAS analyses (PLINK and SKAT-O), and multivariate and mixed model analyses are also recommended.
We are seeking motivated postdocs with strong analytical skills to join our effort and generate novel insights of neurodegeneration with this unique dataset, while working in a highly dynamic multidisciplinary and collaborative environment. The new postdoctoral fellow will join a large team, currently twenty members, which is led by three faculty members and three senior scientists.
Job Location
This position will be located at Dr. Cruchaga’s lab in the NeuroGenomics and Informatics Center (Department of Psychiatry) at Washington University.
Benefits
This position is eligible for full-time benefits. Please click the following link to view a summary of benefits: https://hr.wustl.edu/benefits/.
EOE Statement
The Washington University School of Medicine is renowned for its research cohorts of neurodegenerative disorders, which include clinical, neuroimaging, and fluid biomarker phenotypes. Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
Application
We offer competitive salaries and benefits, please refer to the Human Resources website (http://hr.wustl.edu), and Information on being a postdoc at Washington University in St. Louis can be found at http://postdoc.wustl.edu/prospective-postdocs.
Interested candidates should send a cover letter and a copy of the CV to Pooja Arshanapally (apooja@wustl.edu).
